Product

Human Platelet Lysate (HPL)

Regencore HPL is a defined, xeno-free cell culture supplement intended as a direct replacement for fetal bovine serum (FBS) in the expansion of human mesenchymal stromal cells (MSCs) and other adherent primary cells.

Flagship Product

Research-Grade Human Platelet Lysate

Premium cell culture supplement, manufactured from pooled platelet units collected at FDA-registered US blood centers. Engineered for robust, reproducible cell expansion with preserved cell function.

Xeno-free alternative to FBS — supports translational workflows
Rich in native growth factors (PDGF, TGF-β, IGF, VEGF, bFGF, EGF)
0.22 µm sterile-filtered; tested for bioburden and endotoxin
Lot-tested for MSC proliferation performance
Ships on dry ice; store at –20 °C or below
Certificate of Analysis (CoA) provided with every lot

Request Quote / Sample View Specifications

Available Sizes

Four Bottle Formats

All five formats share the same formulation and labeling — shown to scale below.

60 mL

125 mL

250 mL

500 mL

60 mL

Pilot / Sample Size

Ideal for initial evaluation and screening studies.

125 mL

Small-Scale Research

Perfect for small-scale cultures and pilot experiments.

250 mL

Bench Standard

A popular size for routine laboratory cell-culture work.

500 mL

Research Standard

Our most popular bottle — ideal for ongoing research programs.

Custom Packaging

Need a different volume, kit configuration, or custom labeling? Contact us to discuss custom supply agreements.

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Technical

Product Specifications

Typical specifications for Regencore HPL. A Certificate of Analysis (CoA) is provided with each lot.

Parameter	Specification
Product Name	Human Platelet Lysate (HPL), Research Grade
Source Material	Pooled human platelets from FDA-registered US blood centers
Appearance	Clear to slightly opalescent, amber-yellow liquid
Filtration	0.22 µm sterile-filtered
Formulation	Heparin-free (requires heparin supplementation at use) or heparin-pre-added — specify on order
Viral / Microbial Testing	Donors screened for HIV, HBV, HCV, HTLV, syphilis, and other markers per FDA guidance; bioburden and endotoxin tested
Endotoxin	≤ 5.0 EU/mL
Mycoplasma	Negative
Recommended Use Concentration	5% (v/v) in basal medium (e.g., α-MEM, DMEM, MEM); optimize per cell type
Storage	–20 °C or below; stable for 24 months from date of manufacture
Shipping	Dry ice (frozen)
Intended Use	For Research Use Only. Not for human diagnostic or therapeutic use.

Ordering

Catalog Reference

Quote and availability available on request. Volume discounts are offered for bulk orders and standing supply agreements.